Effectiveness of aldehyde disinfectant "DZPT-2" against the African swine fever virus
Abstract
A.P. Paliy, B.T. Stegniy, A.V. Kuzminov, A.I. Buzun, A.P. Gerilovich, M.V. Bogach and M.Y. Stegniy
We determined the application pattern of the innovative aldehyde disinfectant "DZPT-2" against the African swine fever virus (ASFV). Experiments on virucidal activity of the disinfectant were carried out in strict compliance with biosafety requirements for BSL-3 laboratory (State Institution "Ukrainian Research Anti-Plague Institute named after I.I. Mechnikov Ministry of Health of Ukraine"). We found that "DZPT-2" acts virulently on the causative agent of African swine fever at concentration of 0.5-1.0% of active substance at 1-hour exposure and consumption rate of 300-500 ml/m2. The "DZPT-2" shows virucidal properties against the ASFV at temperature up to minus 26-24 assumed that manufacturing of working solutions was made with 20% solution of antifreeze in concentration of 0.5-1.0% of the active substance at exposure of 1 hour and consumption rate of 300-500 ml/m2. Our results were confirmed during the bioassay as the most sensitive method for determining the viability of the pathogen. "DZPT-2" disinfectant can be used in anti-epizootic measures regarding the African swine fever and could effectively prevent and force the disinfection of livestock and veterinary control facilities. isolated in China. Emerging Microbes & Infections, 8 (1), 438-447. doi: 10.1080/22221751.2019.1590128