Abstract
B.V. Gutyj*, A.Y. Ostapyuk, O.I. Sobolev, V.J. Vishchur, O.P. Gubash, B.M. Kurtyak, Y.V. Kovalskyi, L.M. Darmohray, A.V. Hunchak, O.Y. Tsisaryk, A.R. Shcherbatyy, L.B. Savchuk, T.V. Farionik, O.R. Palyadichuk and K. Hrymak
The article reveals the experimental results of the impact of various doses of cadmium sulfate on morphological and biochemical blood parameters of poultry. The purpose of the research was to figure out how cadmium sulfate at a dose of 2 and 4 mg/kg of body weight effects the morphological parameters of the blood and liver function of the laying chickens. According to the assessment of the morphological analysis of the quantitative and qualitative composition of the blood, it is possible to come to fairly objective conclusions about the functional state of the hematopoietic system of the hen’s body under cadmium burden. Three groups of chickens were formed for the experimant: a control group and two research ones. Chickens of the control group were on a regular diet, they were supplied with nutrition and water without adding cadmium sulfate. Cadmium sulfate was added to drinking water for hens of experimental groups during 30 days. at such doses: the first group – 2 mg/kg, the second group – 4 mg/kg of body weight. Living conditions and microclimate parameters in the room for all groups of birds were the same. The chicken blood was drawn from the axillary veins before drug administering and on the first, seventh, fourteenth, twenty-first and thirtieth days of the experiment. Hematological studies provide an opportunity to study the effect of cadmium on the chicken body in detail, which will lead to more accurate development of a specific prevention and treatment regimen for cadmium toxicosis in poultry.
Feeding the laying chickens with cadmium sulfate at doses of 2 and 4 mg/kg of body weight contributed to a decrease in the number of red blood cells, hemoglobin level and an increase in the number of white blood cells. Changes in morphological parameters are observed on the 21st day of the experiment in chickens of the second experimental group which were given cadmium sulfate at a dose of 4 mg/kg of body weight.
Imposing the body of chickens with cadmium burden contributed to the liver functional state disorder which is demonstrated by the increased activity of aminotransferases in their blood serum. The activity of alanine and aspartate aminotransferases was higher in the serum of chickens of the second experimental group on the 21st and 30th day of the experiment.